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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHMP2A
All Species:
13.03
Human Site:
T38
Identified Species:
22.05
UniProt:
O43633
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43633
NP_055268.1
222
25104
T38
R
E
R
Q
K
L
E
T
Q
E
K
K
I
I
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533565
222
25144
T38
R
E
R
Q
K
L
E
T
Q
E
K
K
I
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB34
222
25115
T38
R
E
R
Q
K
L
E
T
Q
E
K
K
I
I
A
Rat
Rattus norvegicus
Q8CGS4
223
25043
R39
R
Q
I
R
D
I
Q
R
E
E
E
K
V
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZHN1
220
24714
A38
R
E
R
Q
K
L
E
A
Q
E
K
K
I
I
I
Frog
Xenopus laevis
Q6IP52
220
24996
Q38
R
E
R
Q
K
L
E
Q
Q
E
K
K
I
I
A
Zebra Danio
Brachydanio rerio
Q7ZW25
220
25089
Q38
R
E
R
Q
R
L
E
Q
Q
E
K
K
I
I
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651455
256
27330
Q38
R
E
R
M
K
M
E
Q
Q
E
K
K
I
I
A
Honey Bee
Apis mellifera
XP_625164
227
25773
Q38
R
E
R
M
R
M
E
Q
Q
E
K
K
I
I
A
Nematode Worm
Caenorhab. elegans
NP_496717
237
25954
A38
R
E
R
A
R
M
E
A
Q
E
K
K
V
I
A
Sea Urchin
Strong. purpuratus
XP_780405
222
25135
Q38
R
E
K
T
R
M
E
Q
Q
E
K
K
V
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001132529
223
25018
A38
R
E
R
Q
G
L
Q
A
Q
E
K
K
L
I
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SKI2
225
25274
T39
R
E
R
Q
G
L
Q
T
Q
E
K
K
L
I
N
Baker's Yeast
Sacchar. cerevisiae
P36108
232
26272
L41
R
E
K
R
K
L
E
L
Q
D
K
K
L
V
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99
N.A.
99.5
25.1
N.A.
N.A.
88.2
91.8
89.6
N.A.
66
73.5
65.4
69.8
Protein Similarity:
100
N.A.
N.A.
99
N.A.
99.5
52.9
N.A.
N.A.
93.2
95.9
95.5
N.A.
78.5
85.9
80.1
86.9
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
20
N.A.
N.A.
86.6
93.3
86.6
N.A.
80
73.3
66.6
60
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
66.6
N.A.
N.A.
86.6
93.3
93.3
N.A.
86.6
86.6
86.6
86.6
Percent
Protein Identity:
N.A.
55.1
N.A.
55.1
43.5
N.A.
Protein Similarity:
N.A.
74.4
N.A.
75.5
69.4
N.A.
P-Site Identity:
N.A.
66.6
N.A.
73.3
53.3
N.A.
P-Site Similarity:
N.A.
80
N.A.
86.6
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
22
0
0
0
0
0
0
65
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
93
0
0
0
0
79
0
8
93
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
8
0
0
0
0
0
0
58
86
8
% I
% Lys:
0
0
15
0
50
0
0
0
0
0
93
100
0
8
0
% K
% Leu:
0
0
0
0
0
65
0
8
0
0
0
0
22
0
0
% L
% Met:
0
0
0
15
0
29
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
58
0
0
22
36
93
0
0
0
0
0
0
% Q
% Arg:
100
0
79
15
29
0
0
8
0
0
0
0
0
0
8
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% S
% Thr:
0
0
0
8
0
0
0
29
0
0
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
22
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _